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Six months into the COVID-19 crisis, UN Women has played a central part in setting a course for Asia and the Pacific to make gender equality and women’s empowerment central to the pandemic response. We have led the way in providing gender analysis, data and expertise informing decisions about health care, the economy and safety. We have drawn on our unique capacity to back a collective regional response as well as tailored national actions reflecting diverse needs and priorities. In a fast-evolving crisis, we continuously collaborate and exchange what we know, sharing the best strategies within the region and from around the world. This brief provides an overview of UN Women’s response to COVID-19 in the region.